مشخصات پژوهش

صفحه نخست /Fuzzy survival analysis of ...
عنوان
Fuzzy survival analysis of AIDS patients under ten years old in Hamadan-Iran
نوع پژوهش مقاله چاپ شده
کلیدواژه‌ها
Survival analysis, fuzzy logic, computational methods, AIDS, censoring
چکیده
A common and critical issue in survival data analysis is the way in which censored data are handled. The Kaplan-Meier (KM) estimator is a frequently used statistical method in survival analysis that works well with censored data. In small sample sizes with heavy censoring the estimates of KM are not reliable, because the assumptions of KM estimator are violated. In this study, fuzzy logic is used to obtain more reliable estimates when standard statistical methods cannot be used. Data analyzed in this study were the survival times of six AIDS patients under ten years old. One of the patients died after 197 days and the others were censored, giving a censor rate of 83%. The fuzzy-product-limit estimator (FPLE) and a modified FPLE were used to analyze the data. Mean survival time was calculated and associated confidence interval was calculated along with a measure of the amount of “fuzzy information” used to obtain the estimates. In addition, one to ten year survival rates estimated by the KM, FPLE and proposed methods are presented. The result of the simulations showed that the fuzzy methods with few and highly censored data provide more reasonable results than the standard statistical method.
پژوهشگران حسین محجوب (نفر سوم)