مشخصات پژوهش

صفحه نخست /The relationship between ...
عنوان
The relationship between clinicobiochemical markers and depression in women with polycystic ovary syndrome
نوع پژوهش مقاله چاپ شده
کلیدواژه‌ها
Polycystic ovary syndrome, Depression, Obesity, Hirsutism, Complication.
چکیده
Background: Previous studies have demonstrated that clinical features syndrome (PCOS) are associated with a lower degree of health self, and sex satisfaction Objective: Our study aimed to investigate possible associations between depression and different clinicobiochemical markers of PCOS.Materials and Methods: In a cross-sectional analytic study, 120 PCOS women aged 18-45 yr, were enrolled. Beck Depression Inventory was used to assess depression. Also, all participants underwent biochemical studies. Individuals with 15 points and more in Beck test were referred to a psychiatrist to participate in acomplementary interview for the diagnosis of depression based on Diagnostic and Statistical Manual of Mental Disorders IV (DSMIV-TR) criteria Results: Among the study participants, 82 women (68.3%) were non-depressed, and patients (31.7%) had some degrees of depression. According to the psychiatric interview, 10 patients (8.3%) had major depression, 22 patients (18.3%) had minor depression and 6 patients (5%) had dysthymia. We failed to show any significant difference in body mass index, hirsutism, infertility, serum total testosterone, lipid profile, and the homeostasis model assessment of insulin resistance (HOMA-IR) between depressed and non-depressed subjects (p>0.05). Using Spearman correlation, we did not find a positive correlation between BDI scores and clinicobiochemical markers for all PCOS subjects (-0.139≤r≤+0.121, p>0.05 Conclusion: In spite of high rate of depression in women with PCOS, there was no significant association between Clinicobiochemical Markers and depression.
پژوهشگران محمد احسان رحیمی نژاد (نفر اول)، صغری ربیعی (نفر سوم)، فرزانه اثنی عشری (نفر چهارم)، شیوا برزوئی (نفر پنجم)، سید محمد حسینی (نفر ششم به بعد)