مشخصات پژوهش

صفحه نخست /Frequency of viral infections ...
عنوان
Frequency of viral infections and environmental factors in multiple sclerosis.
نوع پژوهش مقاله چاپ شده
کلیدواژه‌ها
Multiple sclerosis; dairy products; environmental exposure; seafood; stress disorders
چکیده
OBJECTIVES: Multiple sclerosis (MS) is a complicated disease which occurs due to relationship between genes and environmental factors that causes tissue damage by autoimmune mechanisms.We investigated and illustrated the hypotheses correlated to the evidence of several putative environmental risk factors for MS onset and progression in this part of Iran. MATERIALS AND METHODS: Univariate logistic regression was used to detect the effects of environmental factors on the risk of MS. Data were analyzed using SPSS version 16. RESULTS: The childhood history of patients with rubella, measles and chickenpox increased the risk of MS significantly. Moreover, low consumption of dairy products, avoidance of seafood consumption, cigarette smoking and exposure to tobacco smoke, stress, anxiety disorders, depress and disturbing thoughts, negative and disturbing thoughts, developing a sudden shock upon hearing bad news, having obsessive-compulsive and being depressed increased the risk of MS significantly. CONCLUSIONS: The results of the current research partially solved the puzzling question of complex interplay between environmental factors and MS disease in this part of Iran. Incorporating these factors enables more powerful and accurate detection of novel risk factors with diagnostic and prognostic methods
پژوهشگران محمد مهدی افتخاریان (نفر اول)، مسعود(بازنشسته) صبوری قناد (نفر دوم)، محمد طاهری(ژنتیک) (نفر سوم)، قدرت اله روشنایی (نفر چهارم)، مهردخت مزده (نفر پنجم)، مهرنوش موسوی (نفر ششم به بعد)، مونا بهمنی هرمز (نفر ششم به بعد)