مشخصات پژوهش

صفحه نخست /A Comparison between Cure ...
عنوان
A Comparison between Cure Model and Recursive Partitioning: A Retrospective Cohort Study of Iranian Female with Breast Cancer
نوع پژوهش مقاله چاپ شده
کلیدواژه‌ها
Model and Recursive Breast Cancer
چکیده
Background. Breast cancer which is the most common cause of women cancer death has an increasing incidence and mortality rates in Iran. A proper modeling would correctly detect the factors’ effect on breast cancer, which may be the basis of health care planning. Therefore, this study aimed to practically develop two recently introduced statistical models in order to compare them as the survival prediction tools for breast cancer patients.Materials and Methods. For this retrospective cohort study, the 18-year follow-up informationof 539breast cancer patientswas analyzedby “ParametricMixtureCureModel” and “Model-BasedRecursive Partitioning.” Furthermore, a simulation study was carried out to compare the performance of mentioned models for different situations.Results. “Model-Based Recursive Partitioning” was able to present a better description of dataset and provided a fine separation of individuals with different risk levels. Additionallythe results of simulation study confirmed the superiority of this recursive partitioning for nonlinear model structures.Conclusion. “Model-Based Recursive Partitioning” seems to be a potential instrument for processing complex mixture cure models. Therefore, applying this model is recommended for long-term survival patients.
پژوهشگران مژگان السادات سیف (نفر اول)، جواد فردمال (نفر دوم)، حسین محجوب (نفر سوم)