مشخصات پژوهش

صفحه نخست /‎ Recurrence in Patients with ...
عنوان
‎ Recurrence in Patients with Bipolar Disorder and Its Risk Factors
نوع پژوهش مقاله چاپ شده
کلیدواژه‌ها
Bipolar Disorder, Ordinal Logistic Regression, Prognosis Factors, Recurrence
چکیده
Objective: The aim of this study was to identify prognosis factors associated with recurrence in patients ‎ with bipolar disorder.‎‎ Method: This retrospective cohort study was conducted in Hamadan Province, the west of Iran. All ‎ patients (n = 400) with bipolar disorder who were hospitalized for the second time or more ‎ during April 2008 to September 2014 were included in this study. Ordinal logistic regression ‎ analysis was employed to determine the effective factors in each recurrence, and odds ratio‎ (OR) and 95% confidence intervals (CI) were obtained.‎ Results: The mean (SD) age of the participants at the entrance to the study was 34.62 (11.68) years. ‎ There was an association between recurrence and type of bipolar disorder (P = 0.033). The ‎ OR of recurrence was 0.28 (95% CI: 0.09, 0.90) for bipolar disorder II; 0.35 (95% CI: 0.13, ‎‎ 0.92) for the patients‎ ‏ ‏ with college education; 0.39 (95% CI: 0.25, 0.60) for employed ‎ patients; 0.55 (95% CI: 0.35, 0.87) for patients who received both drugs and ‎ electroconvulsive therapy, and 1.89 (95% CI: 1.23, 2.92) for patients who stopped using ‎ drugs. In addition, a non-significant association was found between recurrence and age, sex, ‎ marital status, place of residence, season, mood classification and family history of mood ‎ disorder.‎ Conclusion: Type of bipolar disorder and cessation of medication were the leading causes of an increase in ‎ the relapse of the disease. Furthermore, patients who received both drugs and ‎ electroconvulsive therapy had a fewer risk of recurrence.
پژوهشگران رویا نجفی وثوق (نفر اول)، علی قلعه ایها (نفر دوم)، جواد فردمال (نفر سوم)، حسین محجوب (نفر چهارم)