مشخصات پژوهش

صفحه نخست /VALUATION OF WOUND HEALING ...
عنوان
VALUATION OF WOUND HEALING ACTIVITY OF HYDROALCOHOLIC EXTRACT OF BANANA (MUSA ACUMINATA) FRUIT’S PEEL IN RABBIT
نوع پژوهش مقاله چاپ شده
کلیدواژه‌ها
Wound healing, Banana peel, Musa acuminata, Rabbit
چکیده
Banana (Musa acuminata) peel is a rich source of many nutrients and considered high in carbohydrates. It has been traditionaly used to treat diarrhea, anemia and ulcers. Some studies have shown that banana peels possess antioxidant and antiinflammatory properties. This study was performed to evaluate the wound healing activity of banan peels extract (BPE ) in rabbit. For inducing full-thickness wound in rabbits, the excisional wound model was used. The animals were randomly divided into six experimental groups. Negative control, standard and vehicle control groups and treatment groups. All the treatment were apllied topically twice daily. Healing was assessed by wound contraction and re-epithelialization rate and the tensile strength of wound tissue sample . Histopathological examination was also done.The BPE promoted wound healing activity in full-thickness wound model. High rate of wound contraction (P<0.05), significant decrease in epthelialization period (P<0.05) and high skin breaking strength (P<0.01) were obsereved in animals treated with BPE. Histopathological sutudies also showed the wound healing activity of BPE.The results of this study indicated that hydroalcoholic extract of banana peels has a strong potetial for wound healing and it can be used for different types of wounds in human being too
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