چکیده
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Schizophrenia is a destructive clinical syndrome with diverse mental pathologies. Different mechanisms and factors
have a role in this disease. A possible mechanism is that teratogenic viruses cause brain changes and results in the disease
appearance. The schizophrenia patients were diagnosed by psychologists and with the consent of patients, five CC of venous
blood was drawn. Than Serum samples were isolated and immunoglobulin M (IgM) and immunoglobulin G (IgG) antibodies
against herpes simplex virus-1 (HSV-1), herpes simplex virus-2 (HSV-2) and cytomegalovirus (CMV) were quantified by ELISA
sandwich kit. The Results showed that anti-CMV and anti-HSV1 and anti-HSV2 IgG antibodies in schizophrenia patients were
increased significantly ( p < 0.05). The increasing of the anti-HSV2 IgM was also observed but increasing amount of the antiHSV1 IgM was not statistically significant ( p < 0.05). Therefore, as a result of this study CMV and HSV1 and HSV2 infection can probably intensify the symptoms in schizophrenia patients.
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