مشخصات پژوهش

صفحه نخست /Successful pregnancy and live ...
عنوان
Successful pregnancy and live birth after intrauterine administration of autologous platelet-rich plasma in a Successful pregnancy and live birth after intrauterine administration of autologous platelet-rich plasma in a woman with recurrent implantation failure: A case report
نوع پژوهش مقاله چاپ شده
کلیدواژه‌ها
Recurrent implantation failure, Platelet-rich plasma, Embryo transfer, Assisted reproductive technology, Pregnancy outcome, Embryo implantation
چکیده
Background: Platelets contain a significant amount of growth factors that have positive effects on local tissue repair and endometrial receptivity. Case: Here we present a 45-yr-old woman with primary infertility and two failed in vitro fertilization (IVF) cycles who was candidate to receive donor eggs. Five consecutive frozen-thawed embryo transfer cycles with good quality embryos were performed within 2 yr. With the diagnosis of recurrent implantation failure (RIF), the patient was treated for improving endometrial receptivity with intrauterine administration of autologous platelet-rich plasma (PRP), 24 hr before embryo transfer. The patient gave birth to a healthy baby boy weighing 2350 gr in the cesarean section. Conclusion: Extensive literature search suggests that this is the first successful pregnancy after administration of PRP in a woman with RIF. Local administration of PRP before embryo transfer may play a vital role in successful implantation .
پژوهشگران مرضیه سنوئی فریمانی (نفر اول)، جلال پورالعجل (نفر دوم)، صغرا ربیعی (نفر سوم)، مریم بهمن زاده (نفر چهارم)