مشخصات پژوهش

صفحه نخست /Occurrence of bacterial and ...
عنوان
Occurrence of bacterial and toxic metals contamination in illegal opioid-like drugs in Iran: a significant health challenge in drug abusers
نوع پژوهش مقاله چاپ شده
کلیدواژه‌ها
Drug user . Opium . Heroin . Heavy metal toxicity
چکیده
Background The toxic metals and/or bacterial contaminants in illicit drugs are the main health problems in drug users worldwide. Hence, the potential risks of these contaminants were evaluated in some of the illicit drugs during 2015 and 2016. Methods The metals analysis were performed using graphite furnace atomic absorption spectrophotometry. In addition, all microbiological analysis stages, including handling procedures, dilution, and culture media, were conducted in accordance with the US Pharmacopeia (USP) which are harmonized with the European Pharmacopoeia (EP). Results In the present study, the highest lead (Pb; 138.10 ± 75.01 μg/g) and chromium (Cr; 447.38 ± 20.27 μg/g) levels were detected in opium samples. In addition, the highest prevalence of microbial contamination was observed in opium samples, and the lowest was recorded in heroin samples. Clostridium tetani, with about 50%of contaminant, was the most common bacteria in the analyzed samples. Conclusions Our results indicate that Pb exposure as well as bacterial contamination could be the major threats for drug users.
پژوهشگران امیر نیلی احمد آبادی (نفر سوم)