مشخصات پژوهش

صفحه نخست /Oxidative toxic stress in ...
عنوان
Oxidative toxic stress in workers occupationally exposed to ceramic dust: A study in a ceramic manufacturing industry
نوع پژوهش مقاله چاپ شده
کلیدواژه‌ها
Workers, total antioxidant power, oxidative stress
چکیده
Abstract. BACKGROUND:Exposure to compounds used in ceramic industries appears to be associated with induction of oxid toxic stress. Objective: This cross sectional study was undertaken to assess the oxidative toxic stress parameters associ with occupational exposure to ceramic dust. METHODS:Forty ceramic-exposed workers from a ceramic manufacturing industry and 40 unexposed referent sub were studied. A questionnaire containing information regarding demographic variables, occupational history, history of chronic disease, antioxidant consumption, and use of therapeutic drugs was administrated to them. Oxidative toxic s biomarkers including lipid peroxidation (LPO), total antioxidant power (TAP), levels of total Thiol groups (TTG) and cata (CAT) activity were measured. RESULTS:Significant increments in blood LPO levels, CAT activity and concomitant lower TAP were observed in cera exposed workers in comparison to referent group. No statistically significant difference was noted between the means of T levels between the groups. CONCLUSIONS:Findings of the study indicate that occupational exposure to ceramic dust induces oxidative toxic st Supplementation of workers with antioxidants may have beneficial effects on oxidative damages in ceramic industries.
پژوهشگران رشید حیدری مقدم (نفر پنجم)