مشخصات پژوهش

صفحه نخست /Protective effects of green ...
عنوان
Protective effects of green tea on antioxidative biomarkers in chemical laboratory workers
نوع پژوهش مقاله ارائه شده (پوستر یا سخنرانی)
کلیدواژه‌ها
green tea, chemical laboratory workers, oxidative stress
چکیده
Chemical materials are an environmental contaminant, which is extensively used in laboratories, which may cause various forms of health hazards in laboratory workers. Therefore, this toxicity most likely is a result of the oxidative metabolism of chemical to reactive products. As green tea (GT) possesses antioxidant effects, the objective of this study was to examine any amelioration oxidative stress in chemical laboratory workers drinking 1 cup (3g/300 ml water) of freshly prepared tea once daily. Baseline characteristics including age, sex, smoking, fruit consumption and duration of exposure were recorded via questionnaire the subjects. Saliva level oxidative stress parameters such as total antioxidant capacity (TAC), glutathione peroxidase (GPx), catalase (CAT) and superoxide dismutase (SOD) was estimated before and after consumption GT in this workers. Treatment of subjects with GT induced a significant reduction in saliva GPx activity (406.61± 22.07 vs. 238.96 ±16.26 U/L P=0.001) and induction in TAC (0.46 ± 0.029 μmol/ml vs. 0.56 ± 0.031, P=0.016). No statistically significant alteration was found for saliva SOD and CAT (0.080 ± 0.0019 vs. 0.079 ± 0.0014, p>0.05), (‎20.36 ± 0.69 vs. ‎19.78 ± 0.71‎, P>0.05‎) respectively after 28 days treatment by GT. These results demonstrate that drinking GT during chemical exposure can reduce several parameters indicative of oxidative stress. In conclusion, by GT as a dietary supplement, can be a rational protocol to control source of hazards in chemical laboratory workers.
پژوهشگران امید حیدری شایسته (نفر اول)، اکرم رنجبر (نفر دوم)