مشخصات پژوهش

صفحه نخست /The relationship between ...
عنوان
The relationship between serum vitamin D and vitamin B12 levels and diabetic peripheral neuropathy
نوع پژوهش مقاله چاپ شده
کلیدواژه‌ها
Diabetes Mellitus, Diabetic Peripheral Neuropathy, Vitamin D, Vitamin B12
چکیده
Objective: Diabetic peripheral neuropathy (DPN) is one of the most common complications of diabetes. Beside the known factors such as hyperglycemia in the pathogenesis of this complication, other etiologies may play role in the pathogenesis of this complication. The aim of this study was the evaluation of the role of serum vitamin D and vitamin B12 levels in this process. Material and Methods: We enrolled 76 diabetic patients (38 patients with DPN and 38 patients without DPN) that they were age, gender, BMI and duration matched. The diagnosis of DPN was based on nerve conduction studies on sural, peroneal and tibial nerves. Serum vitamin D and vitamin B12 levels were measured in these two groups. Result: Case and control groups had not significant difference in demographic characteristics. Serum vitamin D level was slightly lower in case group (24.1 ± 19.3 ng/ml vs. 24.9 ± 22.3 ng/ml), but had not significant difference (P=0.857). Serum vitamin B12 level was higher in patients with DPN without significant difference in two groups (444.2 ± 273.5 pg/ml vs. 390.4 ± 213.9 pg/ml) (P=0.343). Conclusion: The results of this study showed that serum vitamin D and vitamin B12 levels had not significant difference in patients with and without DPN. Further studies are required to better evaluation of the role of these factors in development and progression of DPN.
پژوهشگران سیدجواد کیانی (تسویه حساب ) (نفر اول)، مهین تزنگ (نفر دوم)، علی تجزیه چی (نفر سوم)، حمیدرضا قاسمی بصیر (نفر چهارم)، دکتر مریم واشقانی ( تسویه حساب) (نفر پنجم)، فرزانه اثنی عشری (نفر ششم به بعد)