مشخصات پژوهش

صفحه نخست /Clinical characteristics and ...
عنوان
Clinical characteristics and outcome of Iranian patients with Kawasaki disease
نوع پژوهش مقاله چاپ شده
کلیدواژه‌ها
Mucocutaneous Lymph Node Syndrome; Children; Coronary Aneurysm; Vasculitis; Iran
چکیده
Abstract: Background: Kawasaki disease (KD) is an acute febrile vasculitis of early childhood and is the leading cause of acquired heart disease in children. The most important complication of Kawasaki disease (KD) is coronary artery aneurysm that may lead to thrombosis and myocardial infarction which occur in 25% of untreated cases but timely treatment decreases it to 2-4%. There is no specific test for KD and its diagnosis is based on clinical and laboratory criteria. Objectives: Since KD is much more common in Iran and other Asian countries, it is necessary to get information about the frequency of these clinical and laboratory findings as well as the coronary aneurysms in our region. Patients and Methods: we retrospectively studied medical records of all children discharged from Besat hospital with final diagnosis of KD from 2004 to 2013. Outpatient clinic documents were also studied. Demographic data, clinical features, laboratory and echocardiographic findings were entered into the forms. Results: 74 patients were discharged with final diagnosis of KD. Out of them43(58.1%) were male and 31(41.9%) were female. seventy seven percent were less than five years. there was no seasonal variability. Forty four cases (59.5%) were diagnosed as complete and 30 cases (40.5%) were diagnosed as incomplete KD. Conjunctivitis occurred in 79% of all patients and considered as the most common clinical finding and peripheral erythema was the least common as it was found in only 23% of cases. Finger desquamation occures in 54% of cases. Leukocytosis was found in 49.3% of cases. In timely treated patients, 11 cases (14/8%) developed coronary artery aneurysms. Conclusions:Sex, age, and seasonal pattern of K.D in Hamadan are similar to other regions; but finger desquamation is less prevalent which diminish its value as a measure for Patients follow up. The most common supplementary laboratory criteria were leukicytosis, thromboscytosis and anemia, which are available via complete bl
پژوهشگران ایرج صدیقی (نفر اول)، منصوره بیگلری (نفر دوم)، حبیب ا... یدالهی فارسانی (نفر چهارم)، اسداله تناسان (نفر پنجم)، سعادت ترابیان ( تسویه حساب ) (نفر ششم به بعد)